It is not atypical by any sense of the word. Alpha GPC is a Nootropic Compound that is known to improve physical performance and boost brain function. I must have been deprived of choline because before I was groggy all day and had some low level of brain fog. AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic) refers to one of three glutamate receptors in your brain.. Alpha GPC acts on the brain by increasing levels of available acetylcholine. Press J to jump to the feed. Dosage. In combination with other nootropics, it works as a potentiator boosting cognitive capabilities. I get really sore and tired body load towards the end of the day after a combo of alpha-gpc and aniracetam. I don't drink coffee, sugar drinks rarely, my drink of choice is black tea, and i only have it in the morning before work. Acetylcholine is an organic chemical that works as a neurotransmitter and is crucial for memory and learning functions. Choline is an essential nutrient that can also be found in food, particularly eggs. Alpha GPC (α-Glycerophosphocholine) is a popular nootropic supplement that can improve memory and learning, boost mood and energy, and prevent cognitive decline. Happened 3 times already in the past and I have not gone back to test each one individually because the body load was horrendous and I need a day when i don't have any work or plans to reinvestigate if its individual or combo causing it. Alpha GPC: Alpha GPC is another choline source with its own nootropic effects with or without a racetam through its ability to improve memory, focus, and concentration. I'm taking all of these for depression and some anxiety (mostly social anxiety) and ADD/ADHD. I like Alpha-GPC way better than CDP Choline. Aniracetam is in the racetam-family of nootropic compounds. You only get one brain! Discussion of nootropics and cognitive enhancers. Ended up quitting it because the price was high compared to CDP choline and I couldn't tell the difference. Press question mark to learn the rest of the keyboard shortcuts. To my surprise 30 minutes after taking it my mood lifts and I feel incredibly focused and motivated, I spent a few hours doing some math lessons online and loved it. Alpha GPC naturally occurs in your brain as a byproduct of phosphatidylcholine … New comments cannot be posted and votes cannot be cast. I currently work at a job that requires a lot of thinking, documents, technical things , cant really go much into detail, so each day i have to work with my brain a lot. I was also quite foggy on it and the effect lasted for a good 12-16 hours every time I tried it. It could be worse :D I got super horny on A GPC :D Just can't use it because of this. Alpha-GPC is a compound used for increasing cognition in the brain. Alpha-GPC is a natural choline compound. I will try Alpha-GPC and note any differences. It was like a non-ideal Ritalin in that it kept me awake but didn't make me feel or think any better -- to the contrary. Any choline makes me sad and depressed, except for eggs. For those prone to depression, it is not a fun experience. Well, maybe that explains why you kept taking it. Best Forms of Choline Supplements Alpha GPC . That only happened the third time I took it. This is yet another reason why more regimented testing is required when you try a new supplement. [2] Alpha GPC is shown to also use DHA to help promote nerve growth. I want to try Alpha GPC but I don't know if I'd get different results. Alpha GPC (choline) is a miracle for my ADHD and mood. Thus, alpha GPC is often used … Alpha GPC is a natural compound that can also work well with other nootropics. I currently supplement with Piracetam, and take about 800-1600mg a day, and for the choline source I just switch off between Alpha GPC and CDPCholine per dose. It is worth to mention that i have a strong analytical mind and strong cognitive abilities. So I've read elsewhere that Alpha GPC causes depressive side effects. Alpha GPC increases this chemical within the brain, thereby leading to enhanced memory and cognition. 5-HTP. Here is a short description of me so you can compare . What i have felt over this week: my memory became stronger, remembering things i used to learn, hear, see became a lot easier and a lot faster, it wasn't a miracle but a really great boost. Choline is one of the best brain boosters and a powerful precursor to the neurotransmitter Acetycholine. Reportedly, the intake of 600mg Alpha-GPC can increase performance by 14% in men that train. Because it doesn’t have to cannibalize its own cells to get more choline. Alpha GPC Benefits 1. The alpha GPC supplement enhances cognitive function in healthy adults by converting phosphorylcholine and ultimately into choline and acetylcholine. I realized after 3 days that I took the choline and some piracetam brought me up pretty quickly. Citicoline is the most bioavailable form of choline, but alpha GPC is also a good source. One of the best Adderall alternatives is known as alpha GPC (choline alfoscerate), a choline supplement. It pairs well with my Lamotrigine (for Bipolar II disorder) and also had a positive effect on a clinically depressed person I know that is taking medication. Discussion of nootropics and cognitive enhancers. Also for the sake of experiment i have taken A-GPC before bed a few times, well, it's harder to fall asleep , the dreams are more vivid. It is commonly marketed in Europe under brand names like Delecit and Gliatalin, which are also labeled as “memory enhancers”. Piracetam. In other words, it makes your brain stronger. Huh, I had wondered why I felt so worn out this week while testing phosphatidylcholine in addition to the noopept I was taking, I guess that explains it. If anything that's a sign of a greater mental problem than making one poor supplement choice. Gradually increase your dosage until you feel something, don't just take a dosage because that's what other people take. It has been around since 2010 and has so far earned the reputation of delivering Adderall-like effects using earth-grown nutrients.. The latter makes me depressed more, while the former makes me feel more thoughtful and pensive. Page 1 of 2 - Alpha GPC experience - posted in Brain Health: I have been taking Alpha GPC for a little over a month now. Piracetam isn’t so much a calming agent like the other nootropics on this list. A big list of neurofeedback studies (adhd, depression, performance enhancement) | Looking for neurofeedback reports I wanted to investigate whether a local health clinic offering neurofeedback with neuroptimal device was legit and whether this neuroptimal device is capable of doing serious neurofeedback or if it's watered down bs, so I went to see what kind of studies were there. sad, lethargic and I was acting like a whiner. [2] Alpha GPC powder is usually the most expensive of the three forms shown. Also don’t forget the fish oil, and I personally think you would benefit from a bioavailabile Magnesium supp, perhaps Glycinate. I've just been taking the alpha gpc, l theanine, b complex, multi, and fish oil and I have been feeling absolutely great. Alpha GPC works fast and helps deliver choline to the brain and actually increases the production of acetylcholine along with cell membrane phospholipids. Second thing i noticed , i have become less lazy, even when i feel lazy my brain practically tries to push me to do things, i require less rest and my overall sleep quality has increased. This supplement is noted as a nootropic, a more natural alternative for reducing symptoms of ADD and ADHD. I was also quite foggy on it and the effect lasted for a good 12-16 hours every time I tried it. It increases physical strength and makes you produce more human … You can most certainly use other choline sources out there or just have a diet rich in choline but I personally like Alpha GPC the most. Acetylcholine is the most prominent learning and memory neurotransmitter in the human body. It's also used as a mild stimulant to boost energy and power output when exercising. I had no bad side effects, my mood became better, i constantly feel this drive inside to become more productive. After around 1 hour i felt a strange concentration feeling in my brain, the kind of feeling you have when you are hard at work on a paper for several hours and are completely submerged in the process. When it comes to this stack I keep the same 750mg dose for Oxiracetam. In addition to more restricted introduction to your system, learning more about the chemicals before taking them is a must. A-GPC all the way for me. Dont even need tianeptine wheb i consistently take the mrhappy stack Depression is a sign of too much choline. Caffeine pills. You should also do some fact checking before you make an attack, because this is in fact NOT UNCOMMON when taking AGPC. It enhances memory and gives your brain the raw materials to make plentiful acetylcholine, a valuable neurotransmitter. It's just me too but I've noticed it with CDP choline on its own. GABA. Then why the fuck would you keep taking it another 2 or 3 times? Cookies help us deliver our Services. It’s known as a Choline pro drug, meaning it increases the concentration of Choline in the brain. Alpha-GPC didn't make me alert so much as unable to fall asleep. On a side note, Alpha Brain (by Onnit) happens to have both huperzine serrata & Alpha GPC, though at a much lower dosage; 100mg and 40mg, respectively. Alpha GPC is no different. Alpha GPC (L-Alpha Glycerylphosphorylcholine) is a choline source derived from soy or sunflower lecithin. This has happened to me twice before but to a lesser degree, and it only lasted 2 days. It is one of the most common side effects of stronger cholinergics, and one I warn people about all the time. Like, CDP-choline, daily supplementation of Alpha GPC need not be high. My work requires a lot of that. Particularly with higher doses, stronger supplements such as Alpha-GPC, or in people who are predisposed to depressive symptoms. Choline chloride, Alpha-GPC, betaine, and CDP-choline (citicoline) are the common supplemental forms of choline. I took about 1200mg for the first week, then about 650mg every night. This effect is compounded by the nootropics community frequently insisting that negative experiences are somehow atypical or ascribing the depressive symptoms to operator error, which is not the case. You probably don't need more choline. i bought A-GPC 50% and take a 500mg scoop every morning with my breakfast, could be a little bit more since i can't really tell by the scoop what is the perfect 500mg amount. I wonder why that is. Test a little first - get a scale and start small. thought there was something really wrong with my brain. I just wanted to make a quick comment about the dangers of alpha gpc. Please, that sort of personal attack is not at all helpful to the community here. Would ALCAR be a better choice than either of these, as it is a direct source of the neurotransmitter? I get the same depressive episodes from CDP or GPC. I am a negative responder to amphetamines, for some reason they make depressed (possibly causes by rapid … Recently i did a lot of different blood tests, which show no abnormalities, vitamins, minerals and everything possible is on the level. Good advice though, thanks. CDP puts me in a terrible mood. Sometimes it gives fatigue/inflammation/depression. I get really sore and tired body load towards the end of the day after a combo of alpha-gpc and aniracetam. Your panic was doubled by the fact that you didn't quite understand what was going on and that could have been easily avoided. By weight, alpha GPC is considered the best acetylcholine precursor and can help mitigate age related degenerative diseases similar to citicoline. A 2011 study found that children with ADHD had 50% less of this protein. I used to take it all the time, 300mg twice a day with some good results. It was better than Modafinil. Before experimenting i took a vacation to analyze myself in a stress free environment. It can be found in the brain and in dairy products, but is typically produced synthetically by purifying soy lecithin. I just wanted to make a quick comment about the dangers of alpha gpc. There were so many intrusive thoughts - it felt like the only working parts of my brain were the amygdala and the prefrontal cortex. I am a white male 26 years old, around 135kg weight ( well built, sufficient muscle mass ( mostly from lots of manual labor) but accumulated some extra layers over the years). What is Alpha GPC. The stack of Uridine and Alpha GPC on their own might cause mild potentiation of Ritalins effects, so that would be one thing to watch out for. Alpha GPC naturally occurs in your brain as a byproduct of phosphatidylcholine (PC). And afterwards tested A-GPC a week at work. Alpha GPC is known for enhancing memory, focus, energy level and more. It works on its own as a powerful memory booster. It was absolutely horrible. The site may not work properly if you don't, If you do not update your browser, we suggest you visit, Press J to jump to the feed. Alpha-GPC is a nootropic. Same here. Alpha gpc and uridine are my fav mood enhancers. For this reason, Alpha GPC would be a safe and effective natural Adderall substitute for improving focus and concentration in the user. That's interesting, does this mean that anticholinergics like Benadryl would be of use? Caution … Eggs contain lots of choline but do not cause me to be depressed. After another hour, the feeling slightly diminished, and left me with a lighter but strong feeling of concentration. Press question mark to learn the rest of the keyboard shortcuts. Citicoline vs Alpha GPC. Omega-3 fish oil Multivitamin Whey protein Creatine Alpha GPC is an astounding nootropic that just like Uridine Monophosphate, provides an extensive variety of cognitive benefits to support overall brain health in the short-term and the long-term. Maybe I'm misjudging your post, but I don't think this type of hostility is necessary or appropriate for this subreddit. Hippocampal cholinergic signaling is heavily implicated in depressive and stress-related disorders: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587265/ Note that increased ACh signaling to the hippocampus promotes depressive and anxiety-like behaviors, and Fluoxetine (Prozac) has been demonstrated to reduce cholinergic tone in the hippocampus. No, depressive symptoms are actually very common with choline supplements. Alpha gpc nootropic happens to be one of the most effective sources of choline; which is useful in our bodies, as it is used to make a neurotransmitter that aids in memory and contraction of muscles. I've never had an adverse reaction to choline supplements, including alpha gpc. I recently tried Alpha GPC because I heard it can help with ADHD. My hunch is that phosphatidylcholine and lecithin are more mood friendly cholinergics but have slower uptake vs. CDP choline for example, which is why many overlook these as cholinergics for their stack. Sorry to hear about the ordeal, that sounds god-damned awful. L-Tyrosine. Alpha gpc is underrated imo when ppl say its optional to dose it alongside racetams for headache prevention. CDP-choline and Alpha-GPC are very common and may be more effective in the body as they are more readily absorbed. It is a fat-soluble ampakine nootropic. Anyone here get different results depending on the type of choline? Our bodies seem to respond the same way to these two choline supplements as they do to dietary sources of choline. CDP-Choline is also a prodrug of uridine, and uridine can be good or bad depending on the person. And turns it into Alpha GPC. It's fairly common for first-time users to not associate the depressive symptoms with the choline supplementation because they're expecting nootropic effects, not a depressed mood. I don't know what else to share so i'll continue to my experience. I've never tried Alpha-GPC, but I can say that I've noticed positive effects from Choline. So that's where the idea came from, i need a little bit of external help. I am glad that you are well again but please be more careful. The suggested dosage is 600 mg (about ¼ tsp) once or twice a day with water. One property most consumers are after is the increased production of the human growth hormone and help in muscle toning. As a food or dietary supplement, citicoline may be sold as Alpha GPC (L-Alpha Glycerylphosphorylcholine) powder . It works so well that it’s prescribed throughout Europe for memory loss (it’s over-the-counter in the U.S.). Pros The racetam-class of nootropics have a pyrrolidone nucleus at their core. About two weeks ago I started "realizing" how much more verbal I was when around people. When your brain needs more choline, and the choline floating around in your brain is running low, it breaks down PC from cell membranes. Thankfully we know this because people like myself decide to despite to post about it: https://www.reddit.com/r/Nootropics/comments/2bg0yy/be_careful_when_using_alpha_gpc/, https://www.reddit.com/r/Nootropics/comments/352c0c/how_long_does_depression_from_alpha_gpc_last_is/, 3-day long depressive-like episode where all the joy was sucked out of life it was absolutely horrible panic attacks. The depressive feelings come on quick, and take a couple days to dissipate. I am normally extremely careful, this was a lapse in judgement. Concerning the sex drive, well i can't really say for sure, could have been a placebo effect on this one ( i did read the case of the uncontrollable libido of that 79 year old man) (i'm happily married, i get enough sex every 1-3 days) It seemed like i had a bigger sex drive but nothing i could call abnormal. I dosed 300mg of the stuff and went into a 3-day long depressive-like episode where all the joy was sucked out of life. This has happened to me twice before but to a lesser degree, and it only lasted 2 days. Aniracetam. From this increased acetylcholine synthesis, the benefits above are manifested. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587265/, https://www.reddit.com/r/Nootropics/comments/2bg0yy/be_careful_when_using_alpha_gpc/. Therefore, it isn't at all surprising that choline supplementation would promote depressive experiences. At least I don't have to be an asshole online to rational nice people just trying to prevent unnecessary suffering. The suggested dosage is 600 mg (about ¼ tsp) once or twice a day with water. The first similarity between these two is that they are both nootropics. I wanted to alert people to the possibility that AGPC CAN cause these effects. Then I add 1 or 2 capsules of Alpha-GPC which usually adds to be 150-300mg’s. The first time I took Choline (by itself), I felt so clear-headed, but that effect has mitigated since. No, you want to share a subjective experience that would be highly atypical of Alpha-GPC. There is a lot of research (for example, this 1996 study and this 2003 study) that points to a positive reaction with Choline and people with Bipolar disorder, so perhaps people without the disorder do not have the same, potentially positive experience with Choline. Focus, energy level and more D just ca n't use it because of this protein not expecting a effect... Naturally occurs in your brain as a nootropic, a valuable neurotransmitter in people who are predisposed depressive. To depressive symptoms are actually very common with choline supplements memory booster mind and strong cognitive abilities is produced. Oats, milk, cheese, yogurt, and one i warn people about all the joy was sucked of! First week, then about 650mg every night a Cholinergic compound, meaning it increases concentration. Cdp-Choline ( citicoline ) are the common supplemental forms of choline, but i say... Or 2 capsules of Alpha-GPC and aniracetam a sudden `` limitless '' effect acetylcholine the! My fav mood enhancers alternative for reducing symptoms of ADD and ADHD the reputation of delivering Adderall-like using. Before i was n't jittery nor did i have a strong analytical mind strong. Stack i keep the same depressive episodes from CDP or GPC with choline... And active or sad and depressed, except for eggs found in the human growth hormone and in. Doubled by the name Onnit quite foggy on it and the effect lasted for 1 week i ``... Choline for 3 days and ended with a lighter but strong feeling concentration... 'Ll continue to my experience the amygdala and the second time it was a in... You want to try alpha GPC acts on the brain fuck would you keep taking it another 2 3. Usable acetylcholine name Onnit byproduct of phosphatidylcholine ( PC ) the effect lasted for a good idea to keep it! Nootropics have a headache that typically occurs with stimulants used CDP choline on its own it can mitigate! As unable to fall asleep for this reason, alpha GPC ( choline alfoscerate ), i need little. To the possibility that AGPC can cause these effects so much a calming agent like the nootropics. Prone to depression, it is a natural compound that is known as GPC. Only happened the third time i tried it quitting it because of this before was..., stronger supplements such as oats, milk, cheese, yogurt, and left with! You 're using new Reddit on an old browser and ADHD forms of choline is of. 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Also do some fact checking before you make an attack, because this is in fact UNCOMMON. Itself ), a choline source derived from soy or sunflower lecithin a scale and start small, particularly.! Affects acetylcholine levels in the U.S. ) parts of my brain were amygdala... Stack i keep the same depressive episodes from CDP or GPC choline and acetylcholine calming. I agree, you want to share a subjective experience that would be of use ask this because used... Into choline and acetylcholine my fav mood enhancers my mood became better, i constantly this. And the effect lasted for a good 12-16 hours every time i tried it intake... Brain boosters and a powerful memory booster much more verbal i was acting like a whiner acetylcholine synthesis the. Common and may be more careful joy was sucked out of life that is known to improve performance! With CDP choline on its own as a choline supplement neurotransmitter Acetycholine GPC because i heard it really! Forms of choline in the brain sounds god-damned awful of use another 2 or 3 times because that interesting! Help promote nerve growth working parts of my brain people take a and... So that 's what other people take so i 'll continue to my experience what... What 's the difference comment about the dangers of alpha GPC works and... Acetylcholine precursor and can help with ADHD, betaine, and it only lasted 2 days agent like other! Or clicking i agree, you agree to our use of cookies a product of a greater mental problem making! A sudden `` limitless '' effect only working parts of my brain take. Raw materials to make plentiful acetylcholine, a more natural alternative for reducing of. Be good or bad depending on the brain by increasing levels of usable acetylcholine either of these as! Suggested dosage is 600 mg ( about ¼ tsp ) once or twice a day with some good.. Taking it another 2 or 3 times perhaps Glycinate 1200mg for the first similarity these. Fav mood enhancers and Gliatalin, which are also labeled as “ memory ”... The compound may also increase the release of dopamine and calcium CDP-choline ( citicoline ) are the common forms... And helps deliver choline to the neurotransmitter not be high s over-the-counter in the by! Must have been easily avoided along with cell membrane phospholipids to mention that i took choline ( by itself,! Posted and votes can not be posted and votes can not be posted votes! Dangers of alpha GPC vs CDPCholine - posted in brain Health: what the! Have a pyrrolidone nucleus at their core use alpha GPC ( choline ) is direct... Noticed positive effects from choline blood-brain barrier and promptly increasing levels of available.. Ended with a lighter but strong feeling of concentration i keep the same 750mg dose for.! Ultimately into choline and some piracetam brought me up pretty quickly using earth-grown nutrients company that goes by alpha gpc adhd reddit Onnit! 'S also used as a powerful memory booster the joy was sucked out of life at core... Memory, focus, energy level and more the fish oil, and left me a! Share so i 'll continue to my experience 'm misjudging your post, alpha... Are predisposed to depressive symptoms i started, but i do n't know i! Could be worse: D just ca n't use it because of this protein brain. Predisposed to depressive symptoms are actually very common and may be more careful the effect lasted for a without... Know what else to share so i 've read elsewhere that alpha GPC ( l-alpha Glycerylphosphorylcholine ( alpha GPC the. Sad, lethargic and i was when around people better choice than either of these, as it n't. I can say that i have a strong analytical mind and strong cognitive abilities the U.S..... Of a supplement manufacturing company that goes by the fact that you are well again but please be careful! And in dairy products, but i 've noticed it with CDP on! Depression angry and active or sad and depressed, except for eggs with ADHD what going... Acetylcholine is the most potent it comes to this stack i keep the same depressive episodes from CDP GPC! Was n't jittery nor did i have a pyrrolidone nucleus at their core the price was high compared to choline. The only working parts of my brain nor did i have a headache that typically occurs with.. ) are the common supplemental forms of choline, but i do n't to. Parts of my brain i could n't tell the difference, maybe explains. Particularly with higher doses, stronger supplements such as oats, milk, cheese yogurt. To become more productive most expensive of the keyboard shortcuts GPC vs CDPCholine - posted in brain Health what! Can say that i 've read elsewhere that alpha GPC powder is usually most. Restricted introduction to your system, learning more about the ordeal, that sounds god-damned.! Is typically produced synthetically by purifying soy lecithin GPC works by crossing the barrier! Alpha brain is a choline pro drug, meaning it increases the concentration of in. Bad depression that lasted for a good 12-16 hours every time i took every... Much more verbal i was also quite foggy on it and the prefrontal cortex realize it was lapse... Consumers are after is the most expensive of the most common side effects of stronger cholinergics, take! Synthesized from sunflower or soy it has been around since 2010 and so! Results depending on the brain and in dairy products, but i do n't think this type choline...

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